🕵️ Upstream BIO, Inc. ($UPB)
SEC insider & ownership activity, last 12 months · CIK 2022626 · every row links its SEC filing
Over the last 12 months insiders sold $77K with no open-market buying against it. Sutherland Everett Rand sold $32K in discretionary trades (Mar–Jun). No red-flag 8-Ks in the window.
Monthly net open-market insider flow, last 12 months (up = net buying)
Insider flow
0 buyers, $0 (0 lots) · 5 sellers, $77K (10 lots)
| Insider | Buys | Bought | Sells | Sold | Last |
|---|---|---|---|---|---|
| Sutherland Everett Rand | 0 | – | 2 | $32K | Jun 16, 2026 |
| Deykin Aaron | 0 | – | 2 | $14K | Jun 16, 2026 |
| Gray Michael | 0 | – | 2 | $13K | Jun 16, 2026 |
| Houghton Adam | 0 | – | 2 | $11K | Jun 16, 2026 |
| Ambrose Allison | 0 | – | 2 | $7K | Jun 16, 2026 |
5%+ holders
| Holder | Stake | Class | Schedule | Event | |
|---|---|---|---|---|---|
| FMR LLC | 14.8% | 13G | Aug 6, 2025 | filing ↗ | |
| Abigail P. Johnson | 14.8% | 13G | Aug 6, 2025 | filing ↗ | |
| Norges Bank | 5.3% | 13G | Oct 24, 2025 | filing ↗ | |
| Decheng Capital Global Life Sciences Fund IV, L.P. | 5.0% | 13G | May 15, 2026 | filing ↗ | |
| Decheng Capital Management IV (CAYMAN), LLC | 5.0% | 13G | May 15, 2026 | filing ↗ | |
| Xiangmin Cui | 5.0% | 13G | May 15, 2026 | filing ↗ |
Planned insider sales (Form 144)
No sale notices filed in the last 12 months.
Material events (8-K)
| Item | Event date | |
|---|---|---|
| Shareholder vote (5.07) | Jun 9, 2026 | filing ↗ |
| Earnings (2.02) | May 13, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | May 13, 2026 | filing ↗ |
| Material agreement (1.01) | Mar 26, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Mar 26, 2026 | filing ↗ |
| Earnings (2.02) | Mar 26, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Mar 26, 2026 | filing ↗ |
| Earnings (2.02) | Feb 11, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Feb 11, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 11, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Feb 11, 2026 | filing ↗ |
| Other events (8.01) | Feb 11, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 11, 2026 | filing ↗ |
| Earnings (2.02) | Nov 5, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Nov 5, 2025 | filing ↗ |
| Reg FD disclosure (7.01) | Sep 2, 2025 | filing ↗ |
| Other events (8.01) | Sep 2, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Sep 2, 2025 | filing ↗ |
| Earnings (2.02) | Aug 6, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Aug 6, 2025 | filing ↗ |