๐Ÿ•ต๏ธ Q32 BIO Inc. ($QTTB)

SEC insider & ownership activity, last 12 months ยท CIK 1661998 ยท every row links its SEC filing

Over the last 12 months insiders sold $460K against $30.0M of open-market buying. Orbimed Advisors LLC bought $15.0M in discretionary trades (May). No red-flag 8-Ks in the window.

Oct 2025: net +$0 Nov 2025: net +$0 Dec 2025: net -$109K Jan 2026: net +$0 Feb 2026: net -$75K Mar 2026: net +$0 Apr 2026: net +$0 May 2026: net +$30.0M Jun 2026: net +$0 Jul 2026: net +$0 Aug 2026: net -$275K Sep 2026: net +$0
Monthly net open-market insider flow, last 12 months (up = net buying)

Insider flow

2 buyers, $30.0M (4 lots) ยท 3 sellers, $460K (8 lots)

InsiderBuysBoughtSellsSoldLast
Orbimed Advisors LLC2$15.0M 0โ€“May 28, 2026
Xu Diyong2$15.0M 0โ€“May 28, 2026
Jodie Morrison0โ€“ 3$286KAug 25, 2026
Lee Kalowski0โ€“ 3$115KAug 25, 2026
Shelia M. Violette0โ€“ 2$59KAug 25, 2026

5%+ holders

HolderStakeClassScheduleEvent
Orbimed Advisors LLC 13.9% 13DJul 16, 2026 filing โ†—
Boxer Capital Management, LLC 13.3% 13GJul 10, 2026 filing โ†—
Boxer Holdings, LP 13.3% 13GJul 10, 2026 filing โ†—
Boxer Holdings GP, LLC 13.3% 13GJul 10, 2026 filing โ†—
Aaron Davis 13.3% 13GJul 10, 2026 filing โ†—
Orbimed Capital GP VII LLC 11.8% 13DJul 16, 2026 filing โ†—
BVF Partners L P/IL 10.0% 13GJun 4, 2026 filing โ†—
BVF INC/IL 10.0% 13GJun 4, 2026 filing โ†—
Mark N. Lampert 10.0% 13GJun 4, 2026 filing โ†—
RA Capital Management, L.P. 9.8% 13GJun 4, 2026 filing โ†—
Peter Kolchinsky 9.8% 13GJun 4, 2026 filing โ†—
Rajeev Shah 9.8% 13GJun 4, 2026 filing โ†—
RA Capital Healthcare Fund, L.P. 9.8% 13GJun 4, 2026 filing โ†—
BVF GP Holdings LLC 9.2% 13GJun 4, 2026 filing โ†—
Opaleye Management Inc. 5.5% 13GJul 31, 2026 filing โ†—
Opaleye, L.P. 5.5% 13GJul 31, 2026 filing โ†—
James Silverman 5.5% 13GJul 31, 2026 filing โ†—
Biotechnology Value Fund L P 5.3% 13GJun 4, 2026 filing โ†—
BVF I GP LLC 5.3% 13GJun 4, 2026 filing โ†—

Planned insider sales (Form 144)

SellerPlannedApprox. sale date
Jodie Morrison$78KDec 2, 2025 filing โ†—
Lee Kalowski$31KDec 2, 2025 filing โ†—

Material events (8-K)

ItemEvent date
Reg FD disclosure (7.01)Sep 14, 2026 filing โ†—
Other events (8.01)Sep 14, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Sep 14, 2026 filing โ†—
Earnings (2.02)Aug 5, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Aug 5, 2026 filing โ†—
Material agreement (1.01)Jul 14, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Jul 14, 2026 filing โ†—
Other events (8.01)Jul 13, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Jul 13, 2026 filing โ†—
Reg FD disclosure (7.01)Jul 13, 2026 filing โ†—
Other events (8.01)Jul 13, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Jul 13, 2026 filing โ†—
Shareholder vote (5.07)Jun 12, 2026 filing โ†—
Material agreement (1.01)May 26, 2026 filing โ†—
Unregistered equity sale (3.02)May 26, 2026 filing โ†—
Other events (8.01)May 26, 2026 filing โ†—
Financial Statements and Exhibits (9.01)May 26, 2026 filing โ†—
Earnings (2.02)May 5, 2026 filing โ†—
Financial Statements and Exhibits (9.01)May 5, 2026 filing โ†—
Other events (8.01)Apr 24, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Apr 24, 2026 filing โ†—
Material agreement (1.01)Mar 27, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Mar 27, 2026 filing โ†—
Earnings (2.02)Mar 10, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Mar 10, 2026 filing โ†—
Material agreement (1.01)Feb 17, 2026 filing โ†—
Other events (8.01)Feb 17, 2026 filing โ†—
Financial Statements and Exhibits (9.01)Feb 17, 2026 filing โ†—
Officer/director changes (5.02)Dec 17, 2025 filing โ†—
Material agreement (1.01)Nov 28, 2025 filing โ†—