🕵️ Praxis Precision Medicines, Inc. ($PRAX)
SEC insider & ownership activity, last 12 months · CIK 1689548 · every row links its SEC filing
Over the last 12 months insiders sold $44.3M with no open-market buying against it. Adage Capital Management, L.P. sold $33.2M (Oct). No red-flag 8-Ks in the window.
Monthly net open-market insider flow, last 12 months (up = net buying)
Insider flow
0 buyers, $0 (0 lots) · 4 sellers, $44.3M (28 lots)
| Insider | Buys | Bought | Sells | Sold | Last |
|---|---|---|---|---|---|
| Adage Capital Management, L.P. | 0 | – | 10 | $33.2M | Oct 16, 2025 |
| Nemiroff Alex | 0 | – | 4 | $4.9M | Nov 20, 2025 |
| Desimone Jill | 0 | – | 12 | $3.6M | Jun 24, 2026 |
| Mastrocola Lauren | 0 | – | 2 | $2.6M | Nov 20, 2025 |
5%+ holders
| Holder | Stake | Class | Schedule | Event | |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 12.3% | 13G | Nov 14, 2025 | filing ↗ | |
| Orbis Investment Management Ltd | 8.9% | 13G | May 15, 2026 | filing ↗ | |
| FMR LLC | 7.7% | 13G | May 6, 2026 | filing ↗ | |
| Abigail P. Johnson | 7.7% | 13G | May 6, 2026 | filing ↗ | |
| Janus Henderson Group PLC | 7.6% | 13G | May 14, 2025 | filing ↗ | |
| Perceptive Advisors LLC | 7.2% | 13G | Feb 17, 2026 | filing ↗ | |
| Joseph Edelman | 7.2% | 13G | Feb 17, 2026 | filing ↗ | |
| Perceptive Life Sciences Master Fund, Ltd. | 7.2% | 13G | Feb 17, 2026 | filing ↗ | |
| Baker BROS. Advisors LP | 6.3% | 13G | May 15, 2026 | filing ↗ | |
| Baker BROS. Advisors (GP) LLC | 6.3% | 13G | May 15, 2026 | filing ↗ | |
| Julian C. Baker | 6.3% | 13G | May 15, 2026 | filing ↗ | |
| Felix J. Baker | 6.3% | 13G | May 15, 2026 | filing ↗ | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 6.2% | 13G | Nov 14, 2025 | filing ↗ | |
| Vanguard Capital Management | 5.1% | 13G | Apr 30, 2026 | filing ↗ |
Planned insider sales (Form 144)
| Seller | Planned | Approx. sale date | |
|---|---|---|---|
| Desimone Jill | $3.6M | Jun 24, 2026 | filing ↗ |
| Nemiroff Alex | $4.9M | Nov 20, 2025 | filing ↗ |
| Mastrocola Lauren | $2.6M | Nov 20, 2025 | filing ↗ |
Material events (8-K)
| Item | Event date | |
|---|---|---|
| Other events (8.01) | Jul 7, 2026 | filing ↗ |
| Other events (8.01) | Jun 29, 2026 | filing ↗ |
| Auditor change (4.01) | Jun 29, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jun 29, 2026 | filing ↗ |
| Other events (8.01) | Jun 22, 2026 | filing ↗ |
| Shareholder vote (5.07) | Jun 10, 2026 | filing ↗ |
| Other events (8.01) | Jun 1, 2026 | filing ↗ |
| Earnings (2.02) | May 7, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | May 7, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | May 7, 2026 | filing ↗ |
| Other events (8.01) | Apr 14, 2026 | filing ↗ |
| Other events (8.01) | Apr 6, 2026 | filing ↗ |
| Earnings (2.02) | Feb 19, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 19, 2026 | filing ↗ |
| Officer/director changes (5.02) | Feb 6, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 6, 2026 | filing ↗ |
| Officer/director changes (5.02) | Jan 8, 2026 | filing ↗ |
| Earnings (2.02) | Jan 6, 2026 | filing ↗ |
| Other events (8.01) | Jan 6, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jan 6, 2026 | filing ↗ |
| Other events (8.01) | Dec 29, 2025 | filing ↗ |
| Other events (8.01) | Dec 9, 2025 | filing ↗ |
| Other events (8.01) | Dec 4, 2025 | filing ↗ |
| Earnings (2.02) | Nov 5, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Nov 5, 2025 | filing ↗ |
| Reg FD disclosure (7.01) | Oct 20, 2025 | filing ↗ |
| Other events (8.01) | Oct 20, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Oct 20, 2025 | filing ↗ |
| Reg FD disclosure (7.01) | Oct 16, 2025 | filing ↗ |
| Other events (8.01) | Oct 16, 2025 | filing ↗ |