🕵️ Karyopharm Therapeutics Inc. ($KPTI)
SEC insider & ownership activity, last 12 months · CIK 1503802 · every row links its SEC filing
Over the last 12 months insiders sold $368K with no open-market buying against it. Richard A. Paulson sold $145K in discretionary trades (Sep–May). T. ROWE Price Investment Management, Inc. trimmed 11.8% → 6.6%. No red-flag 8-Ks in the window.
Monthly net open-market insider flow, last 12 months (up = net buying)
Insider flow
0 buyers, $0 (0 lots) · 7 sellers, $368K (26 lots)
| Insider | Buys | Bought | Sells | Sold | Last |
|---|---|---|---|---|---|
| Richard A. Paulson | 0 | – | 3 | $145K | May 14, 2026 |
| Poulton Stuart | 0 | – | 5 | $59K | May 14, 2026 |
| Rangwala Reshma | 0 | – | 4 | $58K | May 14, 2026 |
| Cheng Sohanya Roshan | 0 | – | 3 | $48K | May 14, 2026 |
| Mano Michael | 0 | – | 3 | $37K | May 14, 2026 |
| Macomber Lori | 0 | – | 1 | $10K | Feb 3, 2026 |
| Abate Kristin | 0 | – | 7 | $10K | May 14, 2026 |
5%+ holders
| Holder | Stake | Class | Schedule | Event | |
|---|---|---|---|---|---|
| Commodore Capital LP | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Commodore Capital Master LP | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Robert Egen Atkinson | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Michael Kramarz | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| RA Capital Management, L.P. | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Peter Kolchinsky | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Rajeev Shah | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| RA Capital Healthcare Fund, L.P. | 9.9% | 13G | Apr 2, 2026 | filing ↗ | |
| Affinity Asset Advisors, LLC | 8.6% | 13G | May 14, 2026 | filing ↗ | |
| Michael Cho | 8.6% | 13G | May 14, 2026 | filing ↗ | |
| Adage Capital Management, L.P. | 8.1% | 13G | May 13, 2026 | filing ↗ | |
| Robert Atchinson | 8.1% | 13G | May 13, 2026 | filing ↗ | |
| Phillip Gross | 8.1% | 13G | May 13, 2026 | filing ↗ | |
| Affinity Healthcare Fund, LP | 7.8% | 13G | Apr 10, 2025 | filing ↗ | |
| Anders Hove | 6.7% | 13G | May 15, 2026 | filing ↗ | |
| T. ROWE Price Investment Management, Inc. | 6.6% | 13G | Jun 5, 2026 | filing ↗ | |
| Blackrock, Inc. | 5.6% | 13G | Jul 28, 2026 | filing ↗ | |
| The Goldman Sachs Group, Inc. | 5.1% | 13G | May 12, 2026 | filing ↗ | |
| Goldman Sachs & Co. LLC | 5.1% | 13G | May 12, 2026 | filing ↗ |
Planned insider sales (Form 144)
No sale notices filed in the last 12 months.
Material events (8-K)
| Item | Event date | |
|---|---|---|
| Officer/director changes (5.02) | Jul 13, 2026 | filing ↗ |
| Officer/director changes (5.02) | May 21, 2026 | filing ↗ |
| Shareholder vote (5.07) | May 21, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | May 21, 2026 | filing ↗ |
| Earnings (2.02) | May 14, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | May 14, 2026 | filing ↗ |
| Other events (8.01) | Mar 27, 2026 | filing ↗ |
| Material agreement (1.01) | Mar 24, 2026 | filing ↗ |
| Unregistered equity sale (3.02) | Mar 24, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Mar 24, 2026 | filing ↗ |
| Other events (8.01) | Mar 24, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Mar 24, 2026 | filing ↗ |
| Material agreement (1.01) | Feb 27, 2026 | filing ↗ |
| Other events (8.01) | Feb 27, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 27, 2026 | filing ↗ |
| Shareholder vote (5.07) | Feb 18, 2026 | filing ↗ |
| Earnings (2.02) | Feb 12, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 12, 2026 | filing ↗ |
| Earnings (2.02) | Jan 12, 2026 | filing ↗ |
| Other events (8.01) | Jan 12, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jan 12, 2026 | filing ↗ |
| Earnings (2.02) | Nov 3, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Nov 3, 2025 | filing ↗ |
| Material agreement (1.01) | Oct 10, 2025 | filing ↗ |
| New financial obligation (2.03) | Oct 10, 2025 | filing ↗ |
| Other events (8.01) | Oct 10, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Oct 10, 2025 | filing ↗ |
| Material agreement (1.01) | Oct 7, 2025 | filing ↗ |
| Earnings (2.02) | Oct 7, 2025 | filing ↗ |
| New financial obligation (2.03) | Oct 7, 2025 | filing ↗ |