🕵️ Denali Therapeutics Inc. ($DNLI)
SEC insider & ownership activity, last 12 months · CIK 1714899 · every row links its SEC filing
Over the last 12 months insiders sold $956K against $40.0M of open-market buying. Baker BROS. Advisors LP bought $40.0M in discretionary trades (Dec). No red-flag 8-Ks in the window.
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Monthly net open-market insider flow, last 12 months (up = net buying)
Insider flow
1 buyer, $40.0M (2 lots) · 3 sellers, $956K (5 lots)
| Insider | Buys | Bought | Sells | Sold | Last |
|---|---|---|---|---|---|
| Baker BROS. Advisors LP | 2 | $40.0M | 0 | – | Dec 11, 2025 |
| Ryan J. Watts | 0 | – | 1 | $581K | Jan 6, 2026 |
| Alexander O. Schuth | 0 | – | 2 | $324K | Jan 6, 2026 |
| Ho Carole | 0 | – | 2 | $52K | Aug 13, 2025 |
5%+ holders
| Holder | Stake | Class | Schedule | Event | |
|---|---|---|---|---|---|
| T. ROWE Price Investment Management, Inc. | 10.2% | 13G | Jul 8, 2026 | filing ↗ | |
| Baillie Gifford & Co | 8.6% | 13G | Feb 12, 2025 | filing ↗ | |
| Blackrock, Inc. | 7.2% | 13G | Apr 17, 2025 | filing ↗ |
Planned insider sales (Form 144)
| Seller | Planned | Approx. sale date | |
|---|---|---|---|
| Carole Ho | $801K | Feb 5, 2026 | filing ↗ |
| Carole Ho | $3.2M | Feb 4, 2026 | filing ↗ |
| Carole Ho | $3.3M | Feb 3, 2026 | filing ↗ |
| Ho Carole | $284K | Jan 6, 2026 | filing ↗ |
| Alexander O. Schuth | $284K | Jan 6, 2026 | filing ↗ |
| Ryan J. Watts | $581K | Jan 6, 2026 | filing ↗ |
| Carole Ho | $36K | Dec 4, 2025 | filing ↗ |
| Carole Ho | $11K | Aug 13, 2025 | filing ↗ |
| Alexander O. Schuth | $40K | Aug 12, 2025 | filing ↗ |
| Ho Carole | $40K | Aug 12, 2025 | filing ↗ |
Material events (8-K)
| Item | Event date | |
|---|---|---|
| Acquisition or disposition (2.01) | Jul 27, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jul 27, 2026 | filing ↗ |
| Material agreement (1.01) | Jun 12, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Jun 12, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jun 12, 2026 | filing ↗ |
| Shareholder vote (5.07) | Jun 3, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jun 3, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | May 21, 2026 | filing ↗ |
| Earnings (2.02) | May 7, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | May 7, 2026 | filing ↗ |
| Agreement terminated (1.02) | Apr 3, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Apr 3, 2026 | filing ↗ |
| New financial obligation (2.03) | Mar 27, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Mar 27, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Mar 25, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Mar 25, 2026 | filing ↗ |
| Earnings (2.02) | Feb 26, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Feb 26, 2026 | filing ↗ |
| Reg FD disclosure (7.01) | Jan 6, 2026 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Jan 6, 2026 | filing ↗ |
| Material agreement (1.01) | Dec 9, 2025 | filing ↗ |
| Other events (8.01) | Dec 9, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Dec 9, 2025 | filing ↗ |
| Reg FD disclosure (7.01) | Dec 4, 2025 | filing ↗ |
| Other events (8.01) | Dec 4, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Dec 4, 2025 | filing ↗ |
| Material agreement (1.01) | Dec 4, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Dec 4, 2025 | filing ↗ |
| Earnings (2.02) | Nov 6, 2025 | filing ↗ |
| Financial Statements and Exhibits (9.01) | Nov 6, 2025 | filing ↗ |